Pentose Phosphate Pathway Quiz Form
Test your knowledge of the pentose phosphate pathway. Please answer all questions to the best of your ability.
Which of the following is the primary purpose of the pentose phosphate pathway?
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Production of NADPH and ribose-5-phosphate
ATP generation via substrate-level phosphorylation
Oxidation of fatty acids
Synthesis of urea
Name the enzyme that catalyzes the first step in the oxidative phase of the pentose phosphate pathway.
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Which molecule is a direct product of the oxidative phase of the pentose phosphate pathway?
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Ribulose-5-phosphate
Fructose-6-phosphate
Glucose-1-phosphate
Pyruvate
List one cellular process that requires NADPH produced by the pentose phosphate pathway.
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Match each enzyme to its function in the pentose phosphate pathway.
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Rows
Catalyzes oxidative decarboxylation
Transfers two-carbon units
Transfers three-carbon units
Enzyme 1
Glucose-6-phosphate dehydrogenase
6-phosphogluconate dehydrogenase
Transketolase
Transaldolase
Glucose-6-phosphate dehydrogenase
6-phosphogluconate dehydrogenase
Transketolase
Transaldolase
Glucose-6-phosphate dehydrogenase
6-phosphogluconate dehydrogenase
Transketolase
Transaldolase
Enzyme 2
Glucose-6-phosphate dehydrogenase
6-phosphogluconate dehydrogenase
Transketolase
Transaldolase
Glucose-6-phosphate dehydrogenase
6-phosphogluconate dehydrogenase
Transketolase
Transaldolase
Glucose-6-phosphate dehydrogenase
6-phosphogluconate dehydrogenase
Transketolase
Transaldolase
Enzyme 3
Glucose-6-phosphate dehydrogenase
6-phosphogluconate dehydrogenase
Transketolase
Transaldolase
Glucose-6-phosphate dehydrogenase
6-phosphogluconate dehydrogenase
Transketolase
Transaldolase
Glucose-6-phosphate dehydrogenase
6-phosphogluconate dehydrogenase
Transketolase
Transaldolase
In which cellular compartment does the pentose phosphate pathway occur?
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Cytoplasm
Mitochondrial matrix
Endoplasmic reticulum
Nucleus
Which of the following best describes the regulation of glucose-6-phosphate dehydrogenase?
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Activated by NADP+ and inhibited by NADPH
Inhibited by ATP
Activated by insulin
Inhibited by glucose
Which of the following is NOT a product or intermediate of the pentose phosphate pathway?
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Sedoheptulose-7-phosphate
Erythrose-4-phosphate
Glyceraldehyde-3-phosphate
Fumarate
Briefly explain why the pentose phosphate pathway is especially important in red blood cells.
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Which enzyme deficiency in the pentose phosphate pathway is most commonly associated with hemolytic anemia?
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Glucose-6-phosphate dehydrogenase
Transketolase
6-phosphogluconate dehydrogenase
Transaldolase
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