How can I change the default email in the From section when replying to someone through the submissions tab?

How do I permanently change the default email used in the From: section? The email listed is the account holder, but I would like to use a different email for all of my replies from the submission form.

I'm sorry, but you cannot change that permanently. The From sender is the primary email address of the account. You can copy/paste the sender's email in the box.